Coffee acts as a laxative by stimulating colon muscle contractions
Evidence from animal studies indicates that coffee and caffeine stimulate colonic smooth muscle contractions and motility, supporting its traditional use as a laxative.
The retrieved literature includes specific in vivo and in vitro animal studies showing that coffee and caffeine stimulate colonic spike activity and muscle contractions, thereby supporting the physiological basis for coffee's laxative effect.
Coffee and caffeine stimulate colonic muscle contractions in animal studies.
M Abo, T Kono, C L Lu, J D Chen. Effects of caffeine on gastrointestinal myoelectric activity and colonic spike activity in dogs.. 2000. https://doi.org/10.1080/003655200750023921
Demonstrates that caffeine increases spike activity and contractility in the colon of dogs.
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Shrilakshmi Hegde, Daniel W Shi, John C Johnson, Ramasatyaveni Geesala, Ke Zhang, You-Min Lin, Xuan-Zheng Shi. Mechanistic Study of Coffee Effects on Gut Microbiota and Motility in Rats.. 2022. https://doi.org/10.3390/nu14224877
Shows that coffee dose-dependently causes colonic muscle contractions in vitro.
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