Cocaine addiction exhibits specific early behavioral and physiological signs

the verdict

SUPPORTED

the evidence backs this

Recorded sources

2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Evidence indicates that cocaine addiction and vulnerability are preceded and accompanied by specific behavioral traits like impulsivity, as well as distinct neurophysiological and inhibitory control alterations.

The analysis

The retrieved literature includes studies showing that traits like impulsivity, novelty preference, and specific neurophysiological deficits (such as impaired inhibitory control and altered dopamine signaling) serve as early indicators or markers associated with cocaine addiction and vulnerability.

Evidence for · 2

Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D2/3 receptor signaling in a rat model of vulnerability to drug abuse

Recorded source metadata

L. Bellés, Andrea Dimiziani, F. Herrmann, N. Ginovart. Early environmental enrichment and impoverishment differentially affect addiction-related behavioral traits, cocaine-taking, and dopamine D2/3 receptor signaling in a rat model of vulnerability to drug abuse. 2021. https://doi.org/10.1007/s00213-021-05971-z

Paper 0 links behavioral traits such as impulsivity and novelty preference to cocaine vulnerability and differential dopamine signaling.

Source citation format

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More for · 1

Preliminary evidence of inhibitory and error-related neural alterations associated with early relapse in cocaine use disorder: A retrospective Go/No-Go ERP study.

Recorded source metadata

Ingels A, Chenut C, Pendry A, Hever F, Dousset C, Kajosch H, Hein M, Campanella S. Preliminary evidence of inhibitory and error-related neural alterations associated with early relapse in cocaine use disorder: A retrospective Go/No-Go ERP study.. 2026. https://doi.org/10.1159/000553386

Paper 4 identifies specific inhibitory control and error-monitoring neural alterations in cocaine use disorder during early detoxification.

Source citation format

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first checked02 Aug 2026

judged → SUPPORTED · 8202 Aug 2026

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