Circularised DNA produces a specific, typical number of agarose gel bands
the verdict
SUPPORTED
the evidence backs this
confidence 82/100
Circularised DNA molecules such as plasmids typically produce specific banding patterns corresponding to their different topological forms and topoisomers when analyzed by agarose gel electrophoresis.
Evidence for · 2
Quantification of DNA by agarose gel electrophoresis and analysis of the topoisomers of plasmid and M13 DNA following treatment with a restriction endonuclease or DNA topoisomerase I
2005 · cited by 13
Paper [1] discusses the analysis of various topological forms of plasmid DNA, including topoisomers, using agarose gel electrophoresis.
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More for · 1
[Formation of cruciform structures in pAO3 plasmid DNA on increasing superhelical density].
1983 · cited by 0
Paper [8] demonstrates that high-resolution gel electrophoresis can resolve the specific topoisomers of circular plasmid DNA into distinct bands.