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the claim
Circular mRNA can be utilized to produce long proteins
the verdict
SUPPORTED
the evidence backs this
confidence 78/100

Recent scientific literature confirms that circular RNAs can be translated into proteins and peptides through various cap-independent mechanisms.

Evidence for · 3
riboCIRC v2.0: an expanded resource for translatable CircRNAs.
2026 · cited by 2
This database resource documents thousands of translatable circRNAs and their encoded finite ORF-encoded peptides.
See more details
More for · 2
Circular RNA as emerging precision therapeutics: from RNA regulation to peptide translation.
2026 · cited by 1
This review highlights that a subset of circular RNAs can be translated to produce bioactive peptides or proteins.
The translational roles of circular RNAs in cancers and their underlying molecular mechanisms.
2026 · cited by 0
This review details how circular RNAs are translated into proteins or peptides through mechanisms such as IRES and m6A elements.
The paper trail · every fact has a biography
first checked01 Aug 2026
judged → SUPPORTED · 7801 Aug 2026
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