Chamomile supplementation promotes relaxation and reduces anxiety.
Clinical and pharmacological evidence indicates that chamomile supplementation possesses anxiolytic properties and promotes relaxation, showing modest effectiveness in reducing symptoms of generalized anxiety disorder.
Multiple clinical trials, including randomized controlled trials, as well as comprehensive reviews, provide empirical support indicating that chamomile extract exhibits anxiolytic and sedative effects. The literature consistently highlights its traditional and scientifically observed role in promoting relaxation and reducing anxiety symptoms.
Sanjay Gupta. Chamomile: A herbal medicine of the past with a bright future (Review). 2010. https://doi.org/10.3892/mmr.2010.377
This review notes that chamomile is traditionally used as a sedative and for conditions such as insomnia and general medicinal properties.
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Amina El Mihyaoui, Joaquim C. G. Esteves da Silva, Saoulajan Charfi, María Emilia Candela Castillo, Ahmed Lamarti, Marino B. Arnao. Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses. 2022. https://doi.org/10.3390/life12040479
The review details chamomile's pharmacological profiles, confirming traditional uses as a sedative and anti-depressant agent.
Jay D. Amsterdam, Yimei Li, Irene Soeller, Kenneth Rockwell, Jun J. Mao, Justine Shults. A Randomized, Double-Blind, Placebo-Controlled Trial of Oral Matricaria recutita (Chamomile) Extract Therapy for Generalized Anxiety Disorder. 2009. https://doi.org/10.1097/jcp.0b013e3181ac935c
This randomized, double-blind, placebo-controlled trial demonstrated that chamomile extract has modest anxiolytic activity in patients with mild to moderate generalized anxiety disorder.
Yun-Lei Dai, Ying Li, Qi Wang, Feng-Jv Niu, Kunwei Li, Yunyu Wang, Jian Wang, Zhou Chang-zheng, Li-Na Gao. Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies. 2022. https://doi.org/10.3390/molecules28010133
This review highlights various pharmacological activities of chamomile, including antidepressant and neuroprotective effects.
Sepideh Miraj, Samira Alesaeidi. A systematic review study of therapeutic effects of Matricaria recuitta chamomile (chamomile). 2016. https://doi.org/10.19082/3024
This systematic review documents the traditional and therapeutic usage of chamomile, including its antidepressant properties.
Jay D. Amsterdam, Qing S. Li, Sharon X. Xie, Jun J. Mao. Putative Antidepressant Effect of Chamomile ( <i>Matricaria chamomilla</i> L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression. 2019. https://doi.org/10.1089/acm.2019.0252
This clinical investigation supports chamomile's anxiolytic activity and indicates potential antidepressant effects in subjects with generalized anxiety disorder.
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