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the claim
Certain species of frogs can change their biological sex
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
3 sources for · 0 against

Multiple scientific studies confirm that certain frog species can undergo biological sex reversal, where individuals develop a phenotypic sex opposite to their genetic sex due to environmental and natural factors.

Evidence for · 3
2019 · cited by 38
This study provides molecular evidence for natural sex reversal (changing phenotypic sex opposite to genotypic sex) in wild populations of green frogs (Rana clamitans).
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The analysis

The retrieved papers include direct empirical evidence of natural and environmentally induced sex reversal in frog species (such as green frogs and agile frogs), as well as comprehensive databases cataloging amphibian sex reversal. Therefore, the claim is supported by the evidence.

More for · 2
2023 · cited by 16
The HerpSexDet database compiles empirical data on herpetological sex determination and documents reports of sex reversal across numerous amphibian species.
2025 · cited by 3
This common-garden experiment demonstrates that agile frogs (Rana dalmatina) can undergo sex reversal in response to environmental conditions such as larval heat stress.
Everything we examined (12)
We also searched for evidence AGAINST this claim, not only for it.
  1. The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event?peer-reviewedno side takennot shown: read and judged not to bear on this claim
  2. Genetic, abiotic and social influences on sex differentiation in cichlid fishes and the evolution of sequential hermaphroditismpeer-reviewedno side takennot shown: read and judged not to bear on this claim
  3. A brief review of vertebrate sex evolution with a pledge for integrative research: towards '<i>sexomics</i>'.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  4. Molecular evidence for sex reversal in wild populations of green frogs (Rana clamitans)peer-reviewedsupports
  5. Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  6. Environmentally-induced sex reversal in fish with chromosomal vs. polygenic sex determinationpeer-reviewedno side takennot shown: read and judged not to bear on this claim
  7. HerpSexDet: the herpetological database of sex determination and sex reversal.peer-reviewedsupports
  8. Temperature- and genotype-dependent stress response and activation of the hypothalamus-pituitary-interrenal axis during temperature-induced sex reversal in pejerrey Odontesthes bonariensis, a species with genotypic and epeer-reviewedno side takennot shown: read and judged not to bear on this claim
  9. Impacts of the synthetic androgen Trenbolone on gonad differentiation and development - comparisons between three deeply diverged anuran families.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  10. Endocrine disruption in teleosts and amphibians is mediated by anthropogenic and natural environmental factors: implications for risk assessment.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  11. Effects of Pharmaceuticals and Endocrine-Disrupting Chemicals on Reproductive Biology of Aquatic Fauna: Penguins as Sentinel Species.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  12. Higher Sex‐Reversal Rate of Urban Frogs in a Common‐Garden Experiment Suggests Adaptive Microevolutionpeer-reviewedsupports
The paper trail · every fact has a biography
first checked06 Aug 2026
judged → SUPPORTED · 8506 Aug 2026
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