Certain parts of the human body possess immune privilege
the verdict
SUPPORTED
the evidence backs this
confidence 88/100
Certain anatomical sites in the human body, such as the brain, eyes, testes, and placenta, are well-documented to possess immune privilege to protect vital tissues from inflammation and immune-mediated damage.
Evidence for · 4
The Kynurenine Pathway Is a Double-Edged Sword in Immune-Privileged Sites and in Cancer: Implications for Immunotherapy.
2016 · cited by 132
The paper explicitly notes that the term 'immune privilege' describes the suppression of inflammatory responses within specific organs protected by anatomic barriers, such as the eyes, brain, placenta, and testes.
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More for · 3
Immune Privilege of Heart Valves.
2021 · cited by 32
This review highlights the eyes, brain, placenta, and testes as classical examples of immune-privileged sites that are evolutionarily adapted to protect vital tissues with limited regenerative capacity.
Integrating miRNA and mRNA Profiling to Assess the Potential miRNA–mRNA Modules Linked With Testicular Immune Homeostasis in Sheep
2021 · cited by 8
The study discusses the mammalian testes as a well-recognized immune-privileged organ that protects autoantigenic germ cells from systemic immune responses.
Kinetics of T cell response in the testes and CNS during experimental autoimmune encephalomyelitis: Simultaneous blood-brain and -testis barrier permeability?
2019 · cited by 5
The article references the central nervous system, testes, and eyes as established immune-privileged sites.