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the claim
Certain chemical reactions occur with zero activation energy
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
2 sources for · 0 against

Chemical reactions with zero or near-zero activation energy are well-documented in specific contexts, such as diffusion-controlled electron transfer and certain barrierless radical recombination steps.

Evidence for · 2
2008 · cited by 460
Demonstrates that certain electron-transfer reactions can occur without an activation barrier when resonance stabilization dominates.
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The analysis

The claim that certain chemical reactions occur with zero activation energy is supported by chemical physics literature on diffusion-controlled electron transfer and barrierless potential energy surface steps (e.g., papers 6 and 10), where activation barriers vanish under high electronic coupling or resonance conditions.

More for · 1
2003 · cited by 245
Shows that the recombination step in cytochrome P450 hydroxylation can occur via virtually barrierless processes.
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first checked31 Jul 2026
judged → SUPPORTED · 9231 Jul 2026
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