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the claim
Certain chemical reactions occur with zero activation energy
the verdict
SUPPORTED
the evidence backs this
confidence 92/100

Chemical reactions with zero or near-zero activation energy are well-documented in specific contexts, such as diffusion-controlled electron transfer and certain barrierless radical recombination steps.

Evidence for · 2
Fresh Look at Electron-Transfer Mechanisms via the Donor/Acceptor Bindings in the Critical Encounter Complex
2008 · cited by 460
Demonstrates that certain electron-transfer reactions can occur without an activation barrier when resonance stabilization dominates.
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More for · 1
A Theoretical Study on the Mechanism of Camphor Hydroxylation by Compound I of Cytochrome P450
2003 · cited by 245
Shows that the recombination step in cytochrome P450 hydroxylation can occur via virtually barrierless processes.
The paper trail · every fact has a biography
first checked31 Jul 2026
judged → SUPPORTED · 9231 Jul 2026
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