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the claim
Cerebrospinal fluid flow is driven by arterial pulsations and respiration
the verdict
SUPPORTED
the evidence backs this
confidence 88/100

Multiple physiological and neuroimaging studies confirm that cerebrospinal fluid flow is actively driven by cardiovascular and respiratory pulsations.

Evidence for · 8
Arterial pulsation—dependent perivascular cerebrospinal fluid flow into the central canal in the sheep spinal cord
1997 · cited by 114
Demonstrates that cerebrospinal fluid flow from perivascular spaces into the central canal is dependent on arterial pulsations.
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More for · 7
Sleep Alters the Velocity of Physiological Brain Pulsations in Humans.
2026 · cited by 4
Shows that cardiovascular and respiratory physiological pulsations act as key drivers of cerebrospinal fluid flow velocity in the brain.
Effect of brief rest on hemodynamics and CSF oscillations across age.
2025 · cited by 2
Identifies cardiac pulsation and respiration as primary drivers of neurofluid oscillations and cerebrospinal fluid dynamics.
Mapping cardiac and respiratory pulsations simultaneously with functional connectivity in the rat brain using zero echo time fMRI.
2026 · cited by 0
Uses fast fMRI to capture cardiac- and respiration-related vascular pulsations contributing to brain fluid dynamics.
Quantifying cerebrospinal fluid flow in pial perivascular spaces of rats.
2026 · cited by 0
Confirms that in vivo cerebrospinal fluid pulsations are substantially synchronized with the heartbeat and tied to artery wall motion.
Quantitative evaluation of low-frequency oscillations using real-time phase-contrast MRI during drowsiness.
2025 · cited by 0
Measures flow rates demonstrating that cardiac pulsations dominate cerebrospinal fluid flow oscillations.
Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions.
2026 · cited by 0
Utilizes multiphysics modeling to show that blood pulsation directly drives cerebrospinal fluid flow and pressure.
Multimodal MR imaging approach to evaluate the interaction between cardiac pulsation and perivascular CSF motion
cited by 0
Finds that changes in cerebral blood volume driven by the cardiac cycle precede perivascular cerebrospinal fluid motion.
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first checked01 Aug 2026
judged → SUPPORTED · 8801 Aug 2026
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