Cells sense their own size using biochemical gradient scaling and molecular titration mechanisms
Cells utilize biochemical gradient scaling and molecular titration mechanisms to sense and maintain their size.
The retrieved literature supports the notion that cells and developing fields use scaling of biochemical gradients and molecular regulators to sense and control size. Paper 3 addresses gradient scaling and size-sensing, while paper 5 explores molecular titration mechanisms of regulators for cell size homeostasis.
Polina S. Timoshina, Andrey G. Zaraisky. Embryonic scaling: morphogen gradients, size sensing, and scaler genes. 2026. https://doi.org/10.3389/fcell.2026.1858676
Discusses how biochemical morphogen gradients scale with spatial size in biological systems.
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Xiangrui Ji, Jie Lin. Implications of differential size-scaling of cell-cycle regulators on cell size homeostasis. 2022. https://doi.org/10.1101/2022.11.30.518453
Demonstrates how molecular mechanisms like differential scaling of cell-cycle regulators control cell size.
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