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the claim

Caffeine has significant effects on the mammalian circulatory system

the verdict

SUPPORTED

the evidence backs this

confidence 83/100

Multiple studies demonstrate that caffeine exerts measurable physiological effects on the mammalian circulatory system, including influences on blood pressure, heart rate, vascular resistance, and autonomic nervous system activity.

Evidence for · 7

The Effects of Caffeine on Blood Platelets and the Cardiovascular System through Adenosine Receptors

2024 · cited by 16

Reviews how caffeine interacts with adenosine receptors to modulate coronary blood flow, peripheral resistance, and heart rate.

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More for · 6

The Effects of Energy Drinks on the Cardiovascular System: A Systematic Review

2025 · cited by 15

Finds that caffeinated energy drinks cause significant cardiovascular effects like increased heart rate, blood pressure, and QTc interval prolongation.

Caffeine and Arrhythmias: A Critical Analysis of Cardiovascular Responses and Arrhythmia Susceptibility

2024 · cited by 9

Examines caffeine's pharmacological properties and its arrhythmogenic potential on the cardiovascular system.

Acute Effects of Caffeine and Taurine on Linear and Nonlinear Measures of the Cardiovascular System in Young Adults

2024 · cited by 6

Demonstrates that acute caffeine consumption significantly affects hemodynamic parameters and heart rate variability.

Dose and Time-Dependent Effects of Caffeine on Cardiovascular Changes Induced by Adenosine

2023 · cited by 2

Shows that caffeine successfully blocks adenosine-induced changes in blood pressure, renal blood flow, and heart rate.

EFFECTS OF CAFFEINE ON BLOOD PRESSURE AND HEART RATE VARIABILITY AT REST AND DURING COLD PRESSOR TEST

2022 · cited by 1

Observes that caffeine alters autonomic nervous system control of heart rate and HRV indices during physical stress.

EFFECT OF CAFFEINE ON SYSTOLIC BLOOD PRESSURE AND HEART RATE IN HEALTHY YOUNG ADULTS

2023 · cited by 0

Notes that caffeine increases systolic blood pressure, mean arterial pressure, and heart rate by acting on vascular receptors and hormones.

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first checked01 Aug 2026

judged → SUPPORTED · 8301 Aug 2026

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