BPA present in metal can linings poses a significant health concern
Evidence consistently shows that bisphenol A (BPA) leaches from metal can linings and food packaging into consumables, acting as an endocrine disruptor that poses significant human health concerns and has prompted stricter global regulations.
The retrieved literature consistently supports the claim that BPA from metal can linings and food packaging migrates into food and poses health concerns, leading to recent regulatory shifts such as EU bans and lowered tolerable daily intake thresholds. There are no refuting papers provided that argue BPA in metal cans is safe or non-migratory.
Błażej Kudłak, Natalia Jatkowska, Paweł Kubica, Galina Yotova, Stefan Tsakovski. Influence of Storage Time and Temperature on the Toxicity, Endocrine Potential, and Migration of Epoxy Resin Precursors in Extracts of Food Packaging Materials. 2019. https://doi.org/10.3390/molecules24234396
Paper [0] demonstrates the migration of epoxy resin precursors, including bisphenols, from food packaging materials like cans into simulation media.
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Fajkić A, Lepara O, Jahić R, Hadžović-Džuvo A, Belančić A, Chupin A, Pavković D, Sher EK. Ultra-Processed Diets and Endocrine Disruption, Explanation of Missing Link in Rising Cancer Incidence Among Young Adults.. 2025. https://doi.org/10.3390/cancers17132196
Paper [1] highlights that bisphenols migrate from containers into food as endocrine-disrupting chemicals that pose building health risks.
Harray AJ, Lucas AD, Herrmann SE, Vlaskovsky PS, Elagali A, Seewoo BJ, Chan DC, Chiarugi D, Kulkarni R, Trevenen M, Wang X, Mueller J, Thomas KV, Papendorf H, Miller C, Gaudieri S, Smith T, Salman S, Murray K, Symeonides C, Dunlop SA, Watts GF, Lucas M. Low-plastic diet and urinary levels of plastic-associated phthalates and bisphenols: the randomized controlled PERTH Trial.. 2026. https://doi.org/10.1038/s41591-026-04324-7
Paper [2] links canned and highly processed foods to higher urinary bisphenol A levels, which were successfully reduced through low-plastic interventions.
Litrenta F, Nava V, Potortì AG, Lo Turco V, Sgrò B, Di Bella G. Bisphenols, Toxic Elements, and Potentially Toxic Elements in Ready-to-Eat Fish and Meat Foods and Their Associated Risks for Human Health.. 2025. https://doi.org/10.3390/toxics13060433
Paper [3] finds BPA present in ready-to-eat foods and notes that updated tolerable daily intake levels indicate a risk to consumers.
Kajiyama T, Kanazaki K, Venkatraman G, Shafinaz Abdul-Rahman P, Matsushima A. Migration of Bisphenol A and Its Derivatives From Epoxy Coatings and Demand for BPA-NI Products: Scientific Insights and Perspectives Leading to Regulation (EU) 2024/3190.. 2025. https://doi.org/10.1002/asia.202500340
Paper [5] reviews the migration of BPA from epoxy can coatings into food and discusses regulatory actions taken to address these health concerns.
Rezapour Z, Arabameri M, Shariatifar N, Hamedi H. Determination of bisphenol a in doogh (a yogurt-based Iranian drink) by magnetic-SPE (MWCNT-Fe<sub>3</sub>O<sub>4</sub>)/GC-MS method and human health risk assessment.. 2025. https://doi.org/10.1038/s41598-025-25638-5
Paper [6] notes that BPA is an endocrine-disrupting chemical posing public health dangers and indicates that consumption from metal containers may endanger human health.
Lovrincevic Pavlovic N, Miskulin I, Kotromanovic Simic I, Dumic L, Kotromanovic D, Miskulin M. Simultaneous Determination of Bisphenol A and Its Analogues in Food Matrixes: Cumulative Exposure Assessment Following New Regulatory Restrictions-A Systematic Review.. 2026. https://doi.org/10.3390/foods15061104
Paper [9] confirms that strict regulatory actions are being prompted because dietary exposure and cumulative intake of bisphenol A present health risks.
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