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Antivenom Therapy: History, Production, and Emerging Innovations.
2026 · cited by 0
Reviews confirm that modern antivenom manufacturing involves refining polyclonal antibodies derived from animals such as sheep, horses, or goats.
Single-reagent one-step procedures for the purification of ovine IgG, F(ab')2 and Fab antivenoms by caprylic acid.
2014 · cited by 0
Details the purification of ovine IgG and antibody fragments (which are derived from sheep blood) to manufacture antivenoms.
An affinity purified ovine antivenom for the treatment of Vipera berus envenoming.
1992 · cited by 0
Describes the development of an ovine (sheep) antivenom utilizing sheep blood/antisera for treating adder envenoming.
Experimental assessment of a new, low-cost antivenom for treatment of carpet viper (Echis ocellatus) envenoming.
1995 · cited by 0
Outlines the production of a low-cost ovine antivenom using sheep antiserum.
Global Sensitivity Analysis for the determination of parameter importance in bio-manufacturing processes.
2008 · cited by 0
Discusses the biomanufacturing process for an ovine-derived rattlesnake antivenom (CroFab) starting from hyperimmunized ovine serum.
The development and evaluation of the efficacy of ovine-derived experimental antivenom immunoserum against Macrovipera lebetina obtusa (MLO) venom.
2021 · cited by 0
Demonstrates the processing and development of an ovine-derived antibody serum (sheep blood products) against viper venom.
A new antivenom to treat eastern coral snake (Micrurus fulvius fulvius) envenoming.
1994 · cited by 0
Evaluates an ovine-based (sheep) Fab antivenom preparation compared to commercial alternatives.