Topical antiperspirants and iontophoresis are well-established, frontline nonsurgical interventions that effectively manage palmar and plantar hyperhidrosis.
The claim states that antiperspirants and iontophoresis effectively treat palmar and plantar hyperhidrosis. Papers [2], [7], and [11] explicitly support nonsurgical modalities such as topical antiperspirants and iontophoresis (device-based interventions/electrical therapies) in managing focal hyperhidrosis including palmar/plantar presentations. There are no refuting papers in the provided set.