Amisulpride treatment leads to elevated prolactin levels

the verdict

SUPPORTED

the evidence backs this

Recorded sources

3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Clinical literature consistently demonstrates that treatment with the atypical antipsychotic amisulpride leads to elevated serum prolactin levels (hyperprolactinemia) due to its dopamine receptor blockade.

The analysis

Multiple retrieved papers (0, 3, 9) explicitly identify amisulpride as an antipsychotic that causes significant prolactin elevation. There is no contradictory evidence in the retrieved set regarding this well-documented adverse effect.

Evidence for · 3

Sex differences in schizophrenia: symptomatology, treatment efficacy and adverse effects.

Recorded source metadata

Moniem I, Kafetzopoulos V. Sex differences in schizophrenia: symptomatology, treatment efficacy and adverse effects.. 2025. https://doi.org/10.3389/fpsyt.2025.1594334

Paper 0 lists amisulpride among antipsychotics that frequently induce hyperprolactinemia.

Source citation format

See more details

More for · 2

Aripiprazole alleviates the high prolactin levels induced by amisulpride via distinct molecular mechanisms: a network pharmacology and molecular docking study.

Recorded source metadata

Yao K, Yang L, Zhang Q, Li C, Tian H, Zhuo C. Aripiprazole alleviates the high prolactin levels induced by amisulpride via distinct molecular mechanisms: a network pharmacology and molecular docking study.. 2025. https://doi.org/10.1186/s12888-025-06818-z

Paper 3 specifically investigates mechanisms of amisulpride-induced prolactin elevation.

Source citation format

Clinical Practice Guideline on the Choice of First Antipsychotic Medicine for Females Experiencing a First-Episode of Psychosis.

Recorded source metadata

Hynes-Ryan C, Keating D, Carolan A, Brand B, Dazzan P, Gaughran F, Hahn M, Halstead S, Harrington SM, Hartnett Y, Kelleher I, Lyne J, McNicholas F, O'Connor K, Perry B, Sadowska E, O'Donoghue B, Sommer IE. Clinical Practice Guideline on the Choice of First Antipsychotic Medicine for Females Experiencing a First-Episode of Psychosis.. 2026. https://doi.org/10.1093/schbul/sbag023

Paper 9 classifies amisulpride among medications carrying a higher risk of prolactin elevation.

Source citation format

The paper trail · every fact has a biography

first checked02 Aug 2026

judged → SUPPORTED · 8202 Aug 2026

More receipts

Is it true that Phonological evolution involves regular processes of phoneme elision, vowel nasalization, and tonogenesis?Is it true that Hemangiomas are treatable with medication?Is it true that Research identifies forms of intelligence that diverge from standard IQ measures?

Random receipt →The Trust Wiki →

Anyone with this link can read the claim and its public receipt, including any personal information in that text. Open permanent receipt.

Check your own claim

Challenge the receipt

I have a source that contradicts this verdict I have a source that supports it No source: request a receipt review Requests are recorded for review. This does not start an automatic check or guarantee a response time.

trust me, bro: win the argument, pass the class, survive peer review.

Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.

This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work · Dispute this receipt