A very low calorie diet can reverse Type 2 diabetes
the verdict
SUPPORTED
the evidence backs this
confidence 87/100
Substantial clinical and experimental evidence demonstrates that very low-calorie diets can effectively reverse hyperglycemia and achieve remission in type 2 diabetes by significantly reducing ectopic fat and restoring insulin sensitivity.
Evidence for · 6
Mechanisms by which a very low calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
2017 · cited by 89
Demonstrates that a very low calorie diet rapidly reverses hyperglycemia and improves insulin sensitivity in animal models of type 2 diabetes.
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More for · 5
Caloric Restriction recovers impaired β-cell-β-cell gap junction coupling, calcium oscillation coordination and insulin secretion in prediabetic mice.
2020 · cited by 37
Shows that caloric restriction reverses weight gain and recovers insulin sensitivity and glucose homeostasis in prediabetic mouse models.
The effectiveness of lifestyle interventions for diabetes remission on patients with type 2 diabetes mellitus: A systematic review and meta-analysis.
2023 · cited by 0
A systematic review and meta-analysis confirming that lifestyle and low-energy diet interventions are effective for achieving type 2 diabetes remission.
Dapagliflozin plus calorie restriction for remission of type 2 diabetes: multicentre, double blind, randomised, placebo controlled trial.
2025 · cited by 0
Induces diabetes remission via calorie restriction combined with pharmaceutical support in overweight or obese patients.
Remission of Type 2 Diabetes with Very Low-Calorie Diets-A Narrative Review.
2021 · cited by 0
A narrative review detailing how very low-calorie diets result in marked improvements in glycemic control and full type 2 diabetes remission.
Diet and exercise in the prevention and treatment of type 2 diabetes mellitus.
2020 · cited by 0
Highlights that calorie-restriction-induced weight loss can lead to remission of type 2 diabetes in a significant portion of patients.