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the claim

A positive attitude enhances immune system functioning through specific neuroendocrine mechanisms

the verdict

SUPPORTED

the evidence backs this

confidence 83/100

Psychoneuroimmunology and clinical research demonstrate that psychological states and mind-body interventions significantly influence immune function via neuroendocrine pathways such as the hypothalamic-pituitary-adrenal axis.

Evidence for · 3

Effects of Mind–Body Interventions on Immune and Neuroendocrine Functions: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2025 · cited by 20

This meta-analysis demonstrates that mind-body interventions positively alter neuroendocrine and immune parameters, reducing inflammatory factors and enhancing immune-activating molecules.

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More for · 2

Beyond tumor biology: nursing interventions for psychological and immune health in cancer patients.

2026 · cited by 1

This review highlights the psychoneuroimmunology research showing bidirectional links between psychological well-being, stress-mediated neuroendocrine pathways, and immune surveillance.

Refractory Keloids and Hypertrophic Scars: Immune Dysregulation and Neuroimmune Mechanisms Underlying Treatment Failure.

2026 · cited by 0

This paper discusses how psychological states and stress-induced hypothalamic-pituitary-adrenal axis dysregulation act as biologically active contributors to immune dysregulation.

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first checked01 Aug 2026

judged → SUPPORTED · 8301 Aug 2026

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